mw+immune+SAC

One of the criteria for the immune response SAC requires you to show your progress in developing your presentation. On this page you should have the following. You should show your planning of the presentation, such as the images chosen and information you want to convey. This includes how you broke up your topic into the various sections. You should also include why you sequenced the images the way you did and the collating of information. It is important that you acknowledge any sources of information (including images) below. You will also need to upload your audio file onto this page.

The reason I have chosen to do this topic is because it was something that not many people chose to do, in addition it will really help my understanding of the process as I realize it is of great importance to the whole immune response, especially when it comes to detecting the pathogen and highlighting the pathogen.

Essentially what I am going to do is: Introduce the immune system and how it detects the invading pathogens. It will then go into detail on the different components of the Humeral response being the memory and plasma b-cells as well as the anti-bodies and their role. After that it will explain how passive immunity doesn't allow for the b-cells to be activated and therefore does not allow for antibodies to be made by the body. This is in the case of a mother with a negative rhesus factor when her child may be positive.

In terms of my pictures I tried to find pictures that would fit in with what I am saying and also to a degree either demonstrate or give an example of what I am saying too.

Where lymphocytes fit into immunity. The 1st, 2nd and 3rd lines of defense, brief descriptions. Explain the difference between non-specific (1st and 2nd) and then specific immunity (3rd) Explain how a macrophage in the 2nd line of defence can detect non-self antigens and what the difference between self and non-self is. Explain what an antigen is The concept of how a macrophage becomes an antigen presenting cell Introduce specific immunity which incorporates the humoral response and cell-mediated response Now go into the detail of how the humoral system works and what it incorporates. The cells used and antibodies that are created The 2 types of b-cells created once activated The antibodies and their function in detecting and helping to kill the invading pathogen Explain the 4 ways in which antibodies can highlight or disable the pathogens: agglutination, precipitation of dissolved antigens, activation of a compliment and neutralization. Identify how passive immunity can occur when antibodies are injected into a person, and use pregnant women as an example of this.
 * Key Concepts to include:**

The main points that I have made throughout the presentation** Humoral Response: Consists of B-cells (plasma and memory) and antibodies
 * Information included:

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B-cells can be used to detect invading pathogens. There are many millions of different types of b-cells that each contain a unique receptor to which an invading pathogen’s antigens will match. In this diagram the b-cells are attaching to the antigens present on a antigen present cell. This is one of the triggers that starts the process of the humoral defence. Another trigger is the b-cell being activated by cytokines released by helper t-cells. However they are apart of the Cell-mediated defence. Once the b-cell has been activated they replicate rapidly into two types of cells. Plasma B-cells and memory b-cells======

The 4 processes that antibodies are used for:
precipitation of dissolved antigens. In this process antibodies group all the toxins together so they can be digested by a macrophage, in addition the antibodies also neutralize the toxins. Neutralisation. Neutralisation disables the pathogen to cause any further damage as their receptors are inhibited by antibodies. Once again the pathogen is engulfed by a macrophage. Activation of a compliment. The antibodies activate a protein in the pathogens membrane and cause cell lyses. Agglutination. Agglutination allows the macrophage to engulf many pathogens rather than just one as the antibodies group them together.

The way in which antibodies are used to help mothers who have a negative rhesus factor:

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The use of antibodies in modern medicine is through the injection of serums into pregnant women. Pregnant women who may have a negative rhesus factor when their child may be positive, can cause problems at birth when some of the child’s blood may pass into the mother. This causes antibodies to be created and therefore in her next child birth if its the same situation, her body may end up attacking the child due to the antibodies created in her previous pregnancy. However to prevent this from occurring, in the mothers first pregnancy, at child birth a serum is injected into the mother containing the antibodies to fight the positive rhesus factor, however this is in fact a passive immunity as the humoral immune defence will not be activated, thus no memory b-cells will be made therefore allowing the mother to have a second child as her body will have no memory of the antigen ever being in her blood.======

I originally tried a practice audio however I found that it was too long, and I had to go back and change what I had originally written. The first one came to 5:37 and the second one 5:10 I am now in the process of cutting out what I feel may be slightly off topic, trying to make some of my points more succinct to allow for less time to be spent on the talking. However I still want to ensure that I am allowing my full understanding of the topic to be shown in the presentation. I finally managed to narrow down my talk to 4:50 I feel that I have included the important points and that they relate well to my topic. In addition I feel that I am using my pictures accurately and that I refer to them accurately.
 * Practice Audio**

I found with some of my pictures there needed to be more to them, I found my self adding in labels in order to make the picture more clear to the viewer. An example of this would be this picture: When looking for my pictures at times i struggled to find pictures that seemed to fit exactly what i was looking for. However at other times there were too many pictures and I had to choose which picture would be most appropriate for what I am talking about. For example I had to choose between this photo and this one. I found that i chose the one on the left because it already had labels as wel as it showed a few different types of white blood cells while the one on the left only showed one.
 * My Pictures**

References and Research

I found that with this topic not much research was required as most of my information was in the text book and course notes that have been handed out. However for my pictures I had many different references

they are the following. Please note I had to make some minor changes to some of the pictures. [|www.faqs.org/health/Sick-V1/Asthma.html] [|www.esf.org/conferences/08210] [|asal-sakti.blogspot.com/] - bone marrow [|faculty.ccri.edu/.../A&P%20cardiovascular.htm] [|www.rowett.ac.uk/edu_web/Gut_reactions3.html] [|www.nlm.nih.gov/.../ency/imagepages/8912.htm] [|www.uspharmacist.com/.../lessonid/105669/] [|www.phasmatodea.org/ap2/immunology2_notes.html] [|uhaweb.hartford.edu/bugl/immune.htm] [|www.uta.edu/chagas/html/biolImS3.html] [|www.ffn.ub.es/ritort/payr.seminars.html] [] [|www.nils.go.jp/.../dma/michan_passione.html] [] [] [|yaabolfasl.blogfa.com/8605.aspx]